| Purity | ≥98% |
| Molecular Weight | 4,113.58 Da |
| Category | GLP-1 Agonists |
Semaglutide
A glucagon-like peptide-1 (GLP-1) receptor agonist used as a research tool to study metabolic regulation and energy homeostasis.
Starting from $44.99
For research use only. Not for human consumption.
Storage Conditions
Store lyophilized powder at −20 °C. Reconstituted solution should be stored at 4 °C and used within 28 days. Do not freeze reconstituted solution.
Research Overview
Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist — a 31-amino acid synthetic peptide analogue of native human GLP-1. It is structurally modified at positions 8 and 26 and conjugated to a C-18 fatty diacid chain, which facilitates albumin binding and significantly extends its pharmacokinetic half-life.
In the research context, semaglutide is used to study the GLP-1 receptor signaling axis, including downstream effects on insulin secretion, glucagon suppression, gastric emptying, and energy intake. GLP-1 receptor agonism has been associated with effects on appetite regulation at the hypothalamic level, making semaglutide a valuable research tool in metabolic biology.
Published research has also examined semaglutide's effects on cardiovascular risk markers, hepatic lipid metabolism, and neuroinflammation in animal models. Its high receptor selectivity and long duration of action make it a well-characterized probe compound for GLP-1 receptor biology.
This product is supplied as lyophilized powder for research use only.
Research use only. This product is intended for in vitro and laboratory research purposes only. It is not approved by the FDA for human or veterinary use. It is not a drug, food, or cosmetic, and may not be misbranded, misused, or sold for purposes other than research.
All information provided is for research and educational purposes only and does not constitute medical advice.